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Eye Drops and Lubricants for Dry Eye

Lubricating eye drops are the everyday foundation of dry eye relief. This is your starting point for understanding the types, choosing the right one, and shopping with confidence. Browse the guides, shop by product type, and find answers to the most common questions.

Four white eye drop bottles of graduated size with teal and indigo caps and plain generic labels, beside a strip of single-use vials, on a pale wooden table by a bright window

Key takeaways

  • Lubricating drops, also called artificial tears, are the first-line, everyday treatment for most dry eye.
  • They come in a few types: watery artificial tears, thicker gels, night-time ointments, and preservative-free versions.
  • If you use drops more than about four times a day, preservative-free is gentler on the eye surface.
  • Drops soothe symptoms and steady the tear film, but they work best alongside the right underlying care.
  • The best choice depends on your type of dry eye, so your eye doctor can help you match a product to your eyes.

Quick answer

Which eye drops should I use?

For most people, start with a quality artificial tear. Choose preservative-free if you dose often or have sensitive eyes, a thicker gel for stronger or longer-lasting relief, and an ointment at night. If your dryness is evaporative, from blocked oil glands, drops help but heat and lid care matter too. Below you will find guides to the best options and a way to shop by product type.

What lubricating drops do

Moisture for the surface, and a steadier tear film

Lubricating eye drops add moisture to the surface of the eye and help a thin or unstable tear film hold together. That relieves the dryness, grittiness, and fluctuating, blurry vision that come when the tear film breaks up too fast. Thinner artificial tears are easy to use throughout the day, gels last longer but can briefly blur vision, and ointments give overnight protection. Preservative-free drops come in single-use vials or special multi-dose bottles and are the gentler choice for frequent use.

Lubricant eye drops are a first-line, foundational therapy for dry eye, and preservative-free options are preferred when drops are used frequently to avoid surface irritation from preservatives. Source: TFOS DEWS III Management and Therapy Report (2025). Full citation at the end of this page.

Shop by Product Type

Browse the full lubricants collection, or jump in by the type that fits your routine.

Artificial Tears

Light, watery drops for regular daytime relief.

Shop Drops

Gels and Ointments

Thicker relief for stronger symptoms and overnight protection.

Shop Gels

Compare and Where to Buy

Weighing brands or deciding where to buy? These guides help you choose and shop with confidence.

Oasis vs iVIZIA

How two popular preservative-free drops fit different routines.

Read the Comparison

iVIZIA vs Optase Intense

Two preservative-free drops compared by active ingredient and fit.

Read the Comparison

Optase Hylo Night vs Refresh PM

Two preservative-free nighttime ointments compared by base, feel, and allergy notes.

Read the Comparison

All Product Comparisons

Every head-to-head comparison and buying guide in one place.

See All Comparisons

Where to Buy Eye Drops by Brand

Buying guides for the most popular dry eye drop brands, with the right formats for each and where to get them.

Oasis Tears

The preservative-free Oasis Tears range, including the Plus formula.

Where to Buy

Systane

From everyday Ultra to Complete, Hydration PF, and nighttime.

Where to Buy

Refresh

From Optive and Relieva to the preservative-free vials and PM.

Where to Buy

Optase

Preservative-free drops, including Hylo, Intense, and MGD Advanced.

Where to Buy

Blink

From Tears and Gel Tears to the preservative-free Boost.

Where to Buy

GenTeal Tears

From the liquid drops to the severe gel and nighttime ointment.

Where to Buy

Biotrue

Hydration Boost, a preservative-free, contact lens friendly drop.

Where to Buy

Freshkote

Freshkote PF, made to support all three layers of the tear film.

Where to Buy

Retaine

The CMC microemulsion drops and the PM nighttime ointment.

Where to Buy

iVIZIA

Preservative-free drops and gel from Thea.

Where to Buy

Dry Eye Rescue Tip

Count your daily drops

If you reach for them more than about four times a day, switch to a preservative-free formula. Frequent exposure to preservatives can irritate an already-stressed eye surface, and preservative-free vials remove that risk entirely.

Not Sure Which Drop Fits?

The right drop depends on your type of dry eye. Dry Eye Rescue works with a network of over 5,000 eye care professionals who can point you to the best fit. Use the Doctor Locator to find one near you.

Patient seated in an exam chair while an eye care professional performs a slit lamp eye exam

Most Common Questions

What is the difference between artificial tears, gels, and ointments?

Artificial tears are light and watery for daytime use, gels are thicker and last longer but can briefly blur vision, and ointments are thickest and best for overnight protection.

Do I need preservative-free drops?

If you use drops more than about four times a day or have sensitive eyes, yes. Preservatives can irritate the surface with frequent use, and preservative-free vials avoid that.

How often can I use lubricating drops?

Most lubricating drops can be used as needed, and preservative-free versions can be used frequently. Follow the label and ask your doctor if you are using them very often.

Can I use these drops with contact lenses?

Some drops are made for use with contacts and others are not, so check the label. When in doubt, ask your eye doctor which is safe with your lenses.

Will drops cure my dry eye?

Drops relieve symptoms and steady the tear film, but they do not fix the underlying cause. They work best alongside the right care for your type of dry eye.

Why do my eyes still feel dry even after using drops?

You may need a different type, such as preservative-free or a thicker gel, or your dryness may be evaporative and also need heat and lid care. An exam can clarify the cause.

Are redness-relief drops the same as lubricating drops?

No. Redness-relief drops whiten the eye but do not treat dryness, and overuse can backfire. For dry eye, choose a lubricating artificial tear instead.

Where can I get help choosing the right drops?

Use the Dry Eye Rescue Doctor Locator to find an eye care professional near you who can match a product to your type of dry eye.

Sources

  1. Tear Film and Ocular Surface Society. TFOS DEWS III Management and Therapy Report. American Journal of Ophthalmology. 2025. ajo.com/article/S0002-9394(25)00274-0

This page is educational and does not replace medical advice from your eye care professional. Individual needs vary, and persistent or worsening symptoms should be evaluated by a professional. If you wear contact lenses or have an eye condition, ask your doctor which drops are right for you. Product and brand names referenced on this site are trademarks of their respective owners.