Eye Drops
Eye Drops & Lubricants
Browse lubricating eye drops, gels and ointments from leading eye-care brands.
Optase
Optase Intense Preservative Free Eye Drops (9.75 mL / 0.33 fl oz, 300 Drops)
10 mL · 1-Month Supply
$23.95$29.99Unit price /UnavailableOasis Medical
Oasis Tears Plus Preservative-Free Eye Drops (10ml Multi-drop Bottle)
10 mL · 20-Day Supply
$24.95$29.99Unit price /UnavailableOptase
Optase MGD Advanced Preservative Free Eye Drops (10 mL, 300 Drops)
2-Month Supply
$23.95$29.99Unit price /UnavailableOasis Medical
Oasis Tears Plus Preservative-Free Lubricant Eye Drops (30 Single-Use Vials)
30 ct · 1-Month Supply
$24.88$29.99Unit price /UnavailableThea
1-Month Supply
$18.95$19.99Unit price /UnavailableOptase
OPTASE Intense Eye Drops Single Dose Units - Preservative Free (30ct. Vials)
30 ct · 1-Month Supply
$23.95$25.99Unit price /UnavailableOasis Medical
Oasis Tears Preservative-Free Lubricant Eye Drops (30 Single-Use Vials)
30 ct · 1-Month Supply
$24.95$28.99Unit price /UnavailableOasis Medical
Oasis Tears Preservative-Free Eye Drops (10mL Bottle)
10 mL · 20-Day Supply
$23.95$28.99Unit price /UnavailableOptase
Optase Hylo Relief Preservative Free Eye Drops (10 mL, 300 Drops)
1-Month Supply
$23.95$24.95Unit price /UnavailableSystane
Systane Complete PF Preservative-Free Lubricant Eye Drops
From $22.95$24.99Unit price /UnavailableThea
10 mL · 20-Day Supply
$17.95$19.99Unit price /UnavailableOptase
Optase Hylo Night Preservative-Free Eye Ointment (5g Tube)
5 g · 3-Month Supply
$16.95$19.99Unit price /UnavailableMuro
Muro 128 Sodium Chloride Hypertonicity Ophthalmic Ointment 5%, Twin Pack, 1/8 oz (3.5 g) Each
8 fl oz · 2-Month Supply
$36.95$39.99Unit price /UnavailableThea
10 mL · 45-Day Supply
$26.95$39.99Unit price /UnavailableMenicon
Menicon LacriPure Sterile Saline Solution - 98 Single-Use 5 mL Vials for Scleral Lenses
5 mL · 3-Month Supply
$37.95$45.99Unit price /UnavailableAbbvie
Refresh PM Lubricant Nighttime Eye Ointment (3.5g)
3.5 g · 1-Month Supply
$12.95$19.99Unit price /UnavailableAbbvie
Refresh Celluvisc Lubricant Eye Drops - 30 Preservative-Free Vials
1-Month Supply
$22.99$27.99Unit price /UnavailableAbbvie
Refresh Optive Mega-3 Preservative-Free Lubricant Eye Drops, 30 Single-Use Vials (0.4 mL Each)
0.4 mL · 1-Month Supply
$23.49$26.99Unit price /UnavailableOCuSOFT
Ocusoft Retaine PM Nighttime Ointment Economy Size 5g
5 g · 45-Day Supply
$15.95$19.99Unit price /UnavailableOptase
Optase Intense Preservative Free Eye Drops 2-Pack (2 x 9.75 mL / 0.33 fl oz, 600 Drops)
2-Month Supply
$42.95$49.00Unit price /UnavailableOptase
Optase MGD Advanced Preservative Free Eye Drops 2-Pack (2 x 10 mL, 600 Drops)
3-Month Supply
$41.95$59.99Unit price /UnavailableOasis TEARS
Oasis Tears Plus Preservative-Free Lubricant Eye Drops, 60 Single-Use Vials (2 Boxes of 30)
60 ct · 2-Month Supply
$44.95Unit price /UnavailableLumify
Lumify Redness Reliever Twin Pack (7.5mL x 2)
7.5 mL · 2-Month Supply
$49.00Unit price /UnavailableLacripure
5 mL · 3-Month Supply
$64.95Unit price /UnavailableOasis Medical
Oasis Tears PF Preservative-Free Lubricant Eye Drops (2 x 10 mL Multi-Dose Bottles)
10 mL · 2-Month Supply
$39.95$49.99Unit price /UnavailableOasis Medical
Oasis TEARS Hypochlorous Eyelid and Lash Cleansing Spray | 55mL
55 mL · 45-Day Supply
$24.95$29.99Unit price /UnavailableLumify
Lumify Redness Reliever Eye Drops, Brimonidine Tartrate 0.025%
From $19.95$24.99Unit price /UnavailableOptase
Optase Hylo Forte Preservative-Free Lubricant Eye Drops (10mL, 300 Drops)
10 mL · 1-Month Supply
$25.95$29.99Unit price /UnavailableSystane
Systane Complete, Lubricant Eye Drops (10ml Bottle)
10 mL · 20-Day Supply
$19.95$19.99Unit price /UnavailableMuro
Muro 128 Sodium Chloride Hypertonicity Eye Drops 5%, Ophthalmic Solution, 0.5 fl oz (15 mL)
15 mL · 1-Month Supply
$28.95$29.99Unit price /UnavailableThea
5 mL · 10-Day Supply
$9.95$15.99Unit price /UnavailableOptase
Optase Comfort Dry Eye Spray, Preservative-Free Lubricant Eyelid Spray (.58 fl oz)
58 fl oz · 1-Month Supply
$22.95$29.99Unit price /UnavailableSystane
Systane Hydration Preservative-Free Lubricant Eye Drops 30ct Vials, 30 Count
30 ct · 1-Month Supply
$22.95$24.99Unit price /UnavailableMuro
Muro 128 Sodium Chloride Hypertonicity Ophthalmic Ointment 5%, 1/8 oz (3.5 g)
8 fl oz · 1-Month Supply
$28.95$34.99Unit price /UnavailableAbbvie
Refresh Relieva Preservative-Free Lubricant Eye Drops (30 Single-Use Vials)
1-Month Supply
$22.95$24.99Unit price /UnavailableRefresh
Refresh Optive Mega-3 Lubricant Eye Drops, 60 Single-Use Vials
30 ct · 2-Month Supply
$39.95Unit price /UnavailablePataday
Pataday Once Daily Relief Extra Strength (2.5ml, 2 Bottles Twin Pack)
2.5 mL · 45-Day Supply
$36.95$39.99Unit price /UnavailableTangible
Tangible Fill Preservative-Free 0.9% Saline Solution for Scleral Lenses, 60 Single Use 5 mL Vials
60 ct · 2-Month Supply
$34.95$39.99Unit price /UnavailablePataday
Pataday Extra Strength 2.5 mL (0.085 fl oz)
2.5 mL · 20-Day Supply
$25.95$29.99Unit price /UnavailableSystane
Systane Complete Preservative-Free Lubricant Eye Drops 30ct Vials
30 ct · 1-Month Supply
$25.95Unit price /UnavailableAbbvie
Refresh Optive Mega-3 Preservative-Free Lubricant Eye Drops (0.4mL Vials, 60-Count)
0.4 mL · 1-Month Supply
$38.95$38.99Unit price /UnavailableBioTrue
Biotrue Hydration Boost Eye Drops, Preservative Free, Soft Contact Lens Friendly (10 mL), Pack of 2
10 mL · 2-Month Supply
$21.95$34.99Unit price /UnavailableEyeganics
Eyeganics Organic Tears USDA Organic Preservative-Free Lubricant Eye Drops, 10 mL
20-Day Supply
$29.00$34.99Unit price /UnavailableOptase
Optase DryEye Kit (A) Heat Mask, Cleansing Wipes, Intense Eye Drops
20-Day Supply
$59.95$69.99Unit price /UnavailableOCuSOFT
OCuSOFT Retaine PM Nighttime Ointment, 2 Pack (2 x 5 g Tubes)
5 g · 3-Month Supply
$29.95$39.99Unit price /UnavailableSystane
Systane PRO PF Multi-Dose Preservative free Lubricant Eye Drops - 10mL
10 mL · 20-Day Supply
$19.95$21.99Unit price /UnavailableAbbvie
Refresh Relieva Preservative-Free Lubricant Eye Drops (10mL Multi-Dose Bottle)
10 mL · 20-Day Supply
$18.95$23.99Unit price /Unavailable
Selecting and using OTC products for dry eyes
A variety of nonprescription products for dry eyes are available, including eyedrops (artificial tears), gels and ointments. Talk with your doctor about which might be best for you. Your doctor should provide you with the product referral pad showcasing which items they have selected for your specific dry eye problem. Be sure to insert the provided coupon code, as this helps report back to your doctor that you are complying with the treatment.
Consider these factors when selecting an OTC lubrication:
- Preservative vs. non preservative drops. Preservatives are added to some eyedrops to prolong shelf life. You can use eyedrops with preservatives up to four times a day. But using the preservative drops more often can cause eye irritation. Most doctors will recommend preservative free as a 1st line treatment.
Non preservative eyedrops come in packages that contain multiple single-use vials such as Blink Tears and now multidose bottles such as Freshkote. After you use a vial, you throw it away. If you rely on eyedrops more than four times a day, no preservative drops are safe and recommended.
- Drops vs. ointments. Lubricating eye ointments coat your eyes, providing longer lasting relief from dry eyes. But these products are thicker than eyedrops and can cloud your vision. For this reason, ointments are best used just before bedtime. Eyedrops can be used at any time and won't interfere with your vision. I-Defense and Hylo Night are the most popular nighttime ointments and are preservative-free.
- Oil Based or Hyaluronic Acid Drops. HA eye drops have increased in patients with dry eye recently due to its water retention and lubrication properties. These drops tend to stay on the eye longer than standard drops thus reducing the number of applications needed throughout the day. Optase Intense and Oasis Tears are the most popular in this category.
- Drops that reduce redness. It's best to avoid these as your solution for dry eyes, as prolonged use can cause more irritation and redness. Lumify uses a different mechanism of action and is considered a better option over Visine or other vasoconstricting products.
- Multi-Layer Artificial Tear. This tear mimics the inner mucin layer by adhering to any dry spots and attracting the water portion of the tear. It also integrates with the oil layer to reduce evaporation, all while increasing the oncotic pressure of the surface of the eye. Increased oncotic pressure draws excess water from the cells onto the surface of the eye, thus increasing tear volume. Freshkote is the only drop in this category and is preservative free and can be used with contact lenses.