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Eye Drops & Lubricants / Refresh

Where to Buy Refresh Eye Drops

Refresh is a long-standing family of artificial tears and lubricant drops from AbbVie, from lightweight daytime drops to lipid-enhanced and overnight options. Here is what the range covers, who each option suits, and where to buy it, including from Dry Eye Rescue, a specialty source trusted by eye care professionals.

Key Takeaways

  • Refresh is a family of lubricant eye drops from AbbVie, sold in multidose bottles, single-use vials, and a nighttime ointment.
  • The range spans light daytime drops, lipid-enhanced formulas for evaporative dryness, and overnight care with PM.
  • Many Refresh options are preservative-free, which suits frequent dosing and sensitive eyes.
  • You can buy Refresh from Dry Eye Rescue, a specialty retailer eye doctors refer patients to, as well as from major retailers.
  • The right drop depends on your type of dry eye, so an eye care professional can confirm the best fit.

Quick Answer: where can I buy Refresh?

You can buy Refresh and the full Refresh range at Dry Eye Rescue, which stocks it because eye care professionals in our network requested it for their patients. Refresh is also sold at major retailers. A specialty source gives you a curated, doctor-backed selection and help choosing the right format, not simply the lowest price.

Best for: light daytime dryness, evaporative dryness that needs a lipid-enhanced drop, sensitive eyes and frequent dosing with the preservative-free vials, and overnight relief with PM.

What Refresh Is

Refresh is a family of lubricant eye drops from AbbVie. The line ranges from light daytime drops, like Refresh Plus and Refresh Tears, to lipid-enhanced formulas such as Refresh Optive Advanced and Optive Mega-3 that target the oily layer of the tear film for evaporative dryness. Refresh Relieva uses HydroCell technology and comes in a preservative-free bottle, and Refresh PM is a nighttime ointment. Many options come in preservative-free single-use vials, which suit sensitive eyes and frequent dosing.

Lubricant drops are a first-line dry eye therapy, and preservative-free options are preferred when drops are used frequently, to avoid surface irritation from preservatives. Source: TFOS DEWS III Management and Therapy Report (2025).

Which Refresh Is Right for You

The Refresh range covers light daytime drops, lipid-enhanced formulas, preservative-free vials, and overnight care. Match the format to your routine.

Refresh Relieva PF, 10ml

Preservative-Free Bottle

Refresh Relieva PF, 10ml

A preservative-free multidose bottle using HydroCell technology for daily dryness and sensitive eyes.

Refresh Optive Advanced, 10ml

Triple-Action

Refresh Optive Advanced, 10ml

A lipid-enhanced drop that targets the water and oil layers of the tear film for evaporative dryness.

Refresh Plus, 30ct Vials

Single-Use Vials

Refresh Plus, 30ct Vials

Lightweight preservative-free vials for frequent dosing and travel.

Refresh PM Ointment

Overnight

Refresh PM Ointment

A preservative-free nighttime ointment for intense overnight dryness.

Where to Buy Refresh

Refresh is available from a few places, and it is fair to say so. You can buy it from large retailers and marketplaces, and you can buy it from Dry Eye Rescue, a specialty dry eye retailer. The reason to choose a specialty source is not that it is always the cheapest, it is that the catalog is curated around dry eye, the products are the ones eye doctors actually refer patients to, and you can pair your purchase with guidance and a way to find a doctor near you.

To buy Refresh from Dry Eye Rescue, shop the Refresh collection for every format, or pick a specific product above.

Comparing Refresh to Other Drops

If you are weighing Refresh against another lubricant drop, our best preservative-free drops guide and best eye drops for dry eye guide walk through how the options fit different routines, without crowning a winner.

Dry Eye Rescue Tip

If your dryness gets worse in wind, air conditioning, or screen time, a lipid-enhanced drop like Refresh Optive Advanced can help by supporting the oily layer of the tear film that slows evaporation.

Not Sure Which Refresh Is Right?

The best drop depends on your type of dry eye. Dry Eye Rescue works with a network of over 5,000 eye care professionals who can confirm the right fit for your eyes. Use the Doctor Locator to find one near you.

DER

Medically reviewed by the DER Medical Advisory Panel

Dry Eye Rescue content is reviewed by the DER Medical Advisory Panel, a group of eye care professionals focused on dry eye and ocular surface care. Dry Eye Rescue helps patients shop trusted eye care products, learn about their condition, and locate a specialist.

Important Disclaimer

This page is educational and does not replace advice from your eye care professional. Individual needs vary, and persistent or worsening symptoms should be evaluated by a professional. Follow the product label, and if you wear contact lenses or have an eye condition, ask your doctor whether a given drop is right for you. Refresh is a trademark of AbbVie. Other product and brand names referenced are trademarks of their respective owners.

Most Common Questions

Where can I buy Refresh eye drops?

You can buy Refresh from Dry Eye Rescue, a specialty dry eye retailer, as well as from major retailers. Shopping a specialty source gives you a curated, doctor-backed selection across the Refresh range.

Is Refresh preservative-free?

Many Refresh products are preservative-free, including the single-use vials and the Relieva preservative-free bottle, while some are preserved multidose bottles. The preservative-free options suit frequent dosing and sensitive eyes.

What is the difference between Refresh Plus, Optive, and Relieva?

Refresh Plus and Tears are light daytime drops, Optive Advanced and Optive Mega-3 are lipid-enhanced for evaporative dryness, and Relieva uses HydroCell technology and comes in a preservative-free bottle.

Should I choose the bottle or the vials?

A multidose bottle is convenient for home or a desk. Single-use vials travel well and keep each dose preservative-free. Many people keep both for different situations.

Is there a Refresh option for nighttime?

Yes. Refresh PM is a preservative-free nighttime ointment for intense overnight dryness.

Can I use Refresh with contact lenses?

Check the product label for contact lens guidance and ask your eye doctor, since not every drop is intended for use directly on lenses.

Is Refresh suitable for moderate to severe dry eye?

Lipid-enhanced formulas like Optive Advanced and the PM ointment target more pronounced or evaporative dryness, while lighter drops suit mild to moderate symptoms. An eye care professional can confirm which fits you.

How does Refresh compare with other lubricant drops?

It fits different routines rather than being better or worse. Our preservative-free drops guide and best eye drops for dry eye guide can help you choose.

How do I know which Refresh is right for my eyes?

An eye care professional can match a drop to your type of dry eye. Use the Dry Eye Rescue Doctor Locator to find one near you.

Get Refresh From a Specialty Source

Shop the full Refresh range, compare your options, or find a doctor who can confirm the right fit.