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Eye Drops & Lubricants / Retaine

Where to Buy Retaine Eye Drops

Retaine is a preservative-free dry eye line from OCuSOFT, including the CMC microemulsion drops and the PM nighttime ointment. Here is what the range covers, who each option suits, and where to buy it, including from Dry Eye Rescue, a specialty source trusted by eye care professionals.

Key Takeaways

  • Retaine is a preservative-free dry eye line from OCuSOFT.
  • Retaine CMC is a microemulsion drop that holds moisture on the surface of the eye for daily dryness.
  • Retaine PM is a preservative-free nighttime ointment for stronger or overnight dryness.
  • You can buy Retaine from Dry Eye Rescue, a specialty retailer eye doctors refer patients to.
  • The right drop depends on your type of dry eye, so an eye care professional can confirm the best fit.

Quick Answer: where can I buy Retaine?

You can buy Retaine at Dry Eye Rescue, which stocks it because eye care professionals in our network requested it for their patients. A specialty source gives you a curated, doctor-backed selection.

Best for: daily dryness and sensitive eyes with the CMC drops, and severe or overnight dryness with the PM ointment.

What Retaine Is

Retaine is a preservative-free dry eye line from OCuSOFT. Retaine CMC is a microemulsion drop, which means tiny droplets help hold both the water and oil parts of the tear film on the surface of the eye, and it comes in single-use vials. Retaine PM is a preservative-free nighttime ointment for stronger or overnight dryness. Because the line is preservative-free, it suits sensitive eyes and frequent dosing.

Lubricant drops are a first-line dry eye therapy, and preservative-free options are preferred when drops are used frequently, to avoid surface irritation from preservatives. Source: TFOS DEWS III Management and Therapy Report (2025).

Which Retaine Option Is Right for You

The Retaine range covers preservative-free CMC drops for daytime use and a nighttime ointment for overnight dryness. Match the format to your routine.

Retaine CMC, 30ct Vials

Preservative-Free Drops

Retaine CMC, 30ct Vials

Preservative-free single-use vials that use a microemulsion to hold moisture on the eye for daily dryness.

Retaine PM Nighttime Ointment

Overnight Ointment

Retaine PM Nighttime Ointment

A preservative-free nighttime ointment for stronger or overnight dryness while you sleep.

Retaine PM, 2-Pack

Value 2-Pack

Retaine PM, 2-Pack

Two tubes of the nighttime ointment for regular overnight use.

Where to Buy Retaine

Retaine is available from a few places, and it is fair to say so. You can buy it from large retailers and marketplaces, and you can buy it from Dry Eye Rescue, a specialty dry eye retailer. The reason to choose a specialty source is not that it is always the cheapest, it is that the catalog is curated, the products are the ones eye doctors actually refer patients to, and you can pair your purchase with guidance and a way to find a doctor near you.

To buy Retaine from Dry Eye Rescue, shop the Retaine collection for every option, or pick a specific product above.

Comparing Retaine to Other Drops

If you are weighing Retaine against another lubricant drop, the CMC microemulsion is its point of difference, since it aims to hold both water and oil on the eye. Our best preservative-free drops guide and best eye drops for dry eye guide walk through how the options fit different routines, without crowning a winner.

Dry Eye Rescue Tip

Ointments are thicker and can blur vision briefly, so the Retaine PM ointment is best at bedtime, with the CMC drops used during the day.

Not Sure Which Retaine Is Right?

The best drop depends on your type of dry eye. Dry Eye Rescue works with a network of over 5,000 eye care professionals who can confirm the right fit for your eyes. Use the Doctor Locator to find one near you.

DER

Medically reviewed by the DER Medical Advisory Panel

Dry Eye Rescue content is reviewed by the DER Medical Advisory Panel, a group of eye care professionals focused on dry eye and ocular surface care. Dry Eye Rescue helps patients shop trusted eye care products, learn about their condition, and locate a specialist.

Important Disclaimer

This page is educational and does not replace advice from your eye care professional. Individual needs vary, and persistent or worsening symptoms should be evaluated by a professional. Follow the product label. Retaine is a trademark of OCuSOFT. Other product and brand names referenced are trademarks of their respective owners.

Most Common Questions

Where can I buy Retaine?

You can buy Retaine from Dry Eye Rescue, a specialty eye care retailer. A specialty source gives you a curated, doctor-backed selection.

Is Retaine preservative-free?

Yes. Both Retaine CMC and Retaine PM are preservative-free, which suits sensitive eyes and frequent dosing.

What is a microemulsion drop?

Retaine CMC is a microemulsion, which means tiny droplets help hold both the water and oil parts of the tear film on the surface of the eye.

What is the difference between Retaine CMC and Retaine PM?

CMC is a daytime drop in single-use vials, and PM is a thicker nighttime ointment for overnight dryness.

When should I use the Retaine PM ointment?

Ointments are thicker and can blur vision briefly, so PM is best used at bedtime.

How often can I use Retaine CMC?

Follow the product label for dosing. Because it is preservative-free, it is well suited to frequent use during the day.

Can I use Retaine with contact lenses?

Check the product label for contact lens guidance and ask your eye doctor, since not every drop is intended for use directly on lenses.

Is Retaine suitable for moderate to severe dry eye?

The CMC drops suit daily dryness and the PM ointment helps with overnight or more pronounced dryness. An eye care professional can confirm the right mix.

How do I know which Retaine is right for my eyes?

An eye care professional can match a product to your type of dry eye. Use the Dry Eye Rescue Doctor Locator to find one near you.

Get Retaine From a Specialty Source

Shop the full Retaine range, compare your options, or find a doctor who can confirm the right fit.