EPA and DHA
The two omega-3s eye care professionals talk about most. They come from fish and algae and are supplied directly.
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Buying Guide
Omega supplements are one of the most commonly recommended additions to a dry eye routine. Here is what the consensus guidelines say, how the products actually differ from each other, and how to decide with your eye doctor.

Key takeaways
Quick answer
The one your eye doctor agrees fits your case, taken consistently. Products differ in source, in how much EPA and DHA a serving actually delivers, in chemical form, and in format. Read the supplement facts panel, compare the cost per day rather than the shelf price, and bring the bottle to your next exam.
The two omega-3s eye care professionals talk about most. They come from fish and algae and are supplied directly.
A plant omega-3 from sources such as flaxseed. The body converts it to EPA and DHA, but inefficiently.
An omega-6 found in black currant seed and evening primrose oil, which appears in some dry eye formulas.
Omegas are taken by mouth and work on a much slower timescale than a drop or a warm compress.
What the guidelines say
The TFOS DEWS II Management and Therapy Report is the international consensus review of dry eye treatment, and it includes essential fatty acid supplementation in its staged management algorithm. That report also notes broadly that many of the treatments in common use for dry eye lack the level of evidence needed to recommend them outright, often because of study design limitations rather than because they have been shown not to work.
That is the honest position for a supplement category. Omega supplementation is an established part of how dry eye is managed in practice, and whether it belongs in your routine is a clinical judgment your own eye doctor is in a position to make and a product page is not.
If you take one thing from this page, take this: bring the question to your eye exam. Your doctor knows what is actually driving your symptoms, what you have already tried, and what else you are taking.
Source: TFOS DEWS II Management and Therapy Report (2017). Full citation at the end of this page.
This is the part that is worth reading before you buy, and it is mostly a matter of reading the supplement facts panel rather than the front of the box. Four things distinguish one product from another. Cost per day is usually a fairer comparison than the price on the shelf, since bottle sizes and serving sizes vary widely.
Supplements are not risk free and they interact with real medications. Bring the actual bottle, or a photo of the label, to your next appointment.
Listed in order of how often Dry Eye Rescue customers buy them. Descriptions are the manufacturer's own. Which one suits you is a question for your eye doctor.
About the Product Available options: 180ct 2 Month Supply, 270ct 3 Month, 90ct 1 Month....
About the ProductDry Eye Omega Benefits Liquid is a liquid dietary supplement of fish oil...
About the ProductAvailable options: 120ct, 60ct.120ctProOmega 2000 is a lemon flavored omega-3 fish oil supplement...
About the ProductRetaine Flax Omega is a dietary supplement in softgel form, supplied as 120...
About the ProductEyePromise EZ Tears is a dietary supplement supplied as softgels. One bottle contains...
About the ProductFortifeye Black Currant Seed Oil GLA is a black currant seed oil dietary...
How long before you would know
Omega supplements are not a fast-acting treatment. Patients who try them are usually asked to give it several months of consistent daily use before judging, and to keep the rest of their routine steady in the meantime so they can tell what is doing what. Changing three things at once tells you nothing about any of them.
An omega supplement is one line in a dry eye plan, not the plan. A typical at-home routine looks more like this.
A warm compress or heated eye mask, if meibomian gland dysfunction is part of the picture.
Lid hygiene after warming the lids.
Preservative-free artificial tears during the day as needed.
An omega supplement, if you and your doctor decide to include one.
An eye exam to confirm what is actually driving the symptoms, and to discuss prescription or in-office options if the at-home routine is not enough.
Whether an omega supplement belongs in your routine depends on what is actually driving your dry eye, and on the other medications you take. An exam answers both. Dry Eye Rescue works with a network of over 5,000 eye care professionals.

Essential fatty acid supplementation is an established part of how dry eye is managed in practice, and it appears in the TFOS DEWS II staged management algorithm. That same consensus report is candid that many treatments in common use for dry eye, this category included, do not yet have the level of published evidence needed for an outright recommendation. So the useful answer is not yes or no: it is a question for the eye doctor who knows your case.
There is no single dose that applies to everyone, and this is a question for your eye doctor or physician rather than a product page. What you can do before that conversation is read the supplement facts panel on any product you are considering: check the EPA and DHA figures per serving, and check how many softgels make up one serving. Those two numbers are what let you compare products meaningfully.
They are not the same thing. Fish oil and algae oil supply EPA and DHA directly. Flaxseed supplies ALA, which the body converts to EPA and DHA inefficiently. Algae-based products are the usual route for people who are vegan or avoiding fish. Which is appropriate for you is worth asking your doctor.
Omega supplements are not fast acting. Patients who try one are typically asked to take it consistently for several months before judging, and to keep the rest of their routine unchanged during that time so it is possible to tell what is doing what.
Check first. Talk to your doctor or pharmacist before starting if you take a blood thinner or antiplatelet medication, have a fish or shellfish allergy, have surgery scheduled, are pregnant or nursing, or already take another supplement containing fish oil. Bringing the bottle or a photo of the label to your appointment is the easiest way to have that conversation.
Price tracks a number of things: EPA and DHA content per serving, the chemical form used, sourcing and purity testing, and the number of servings in the bottle. A higher price does not by itself mean a product will suit you better. Compare the supplement facts panels and the cost per day rather than the price on the shelf.
An omega supplement is one line in a dry eye plan, not the plan. Most routines still include artificial tears during the day, lid hygiene, and a warm compress if meibomian gland dysfunction is part of the picture. An eye exam is what tells you which of those matter most for you.
Sources
Educational information only. This page does not replace medical advice from your eye care professional or healthcare provider. Dietary supplements are not intended to diagnose, treat, cure, or prevent any disease, and these statements have not been evaluated by the Food and Drug Administration. Talk to your doctor before starting any supplement, particularly if you take other medications. Product and brand names referenced are trademarks of their respective owners.