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Preservative Free PF in Multi-Dose Bottle Solutions

25 products

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Preservative Free (PF) in Multi-dose Bottle – Experience gentle, long-lasting relief without irritation. Our Preservative-Free Multi-Dose Eye Drops Collection is designed specifically for individuals who suffer from dry eyes, allergies, or sensitivity to preservatives. This collection provides long-lasting relief from discomfort in a convenient multi-dose bottle that eliminates the need for irritating preservatives. Utilizing advanced one-way valve technology, these bottles ensure sterility for easy, mess-free application.

Why Choose Preservative-Free Multi-Dose Eye Drops?

Traditional eye drops containing preservatives can lead to redness, irritation, and potential long-term damage to your eyes, particularly for those with chronic dry eye or frequent drop usage. Our preservative-free, multi-dose bottles provide:

  • Safe, irritation-free hydration for sensitive eyes
  • Longer-lasting relief without the hassle of single-use vials
  • Sterile, contaminant-free dispensing with every drop
  • Reduced risk of allergic reactions and ocular surface damage
  • Eco-friendly and cost-effective compared to single-use options

Explore Our Preservative-Free Multi-Dose Eye Drops

Our collection includes a variety of ophthalmologist-recommended, preservative-free eye drops for all-day comfort and hydration:

  • Dry Eye Relief Drops – Soothes and replenishes moisture for dry, irritated eyes.
  • Allergy Relief Drops – Provides itch and redness relief without preservatives.
  • Contact Lens-Compatible Drops – Safe for use with contacts to rehydrate and refresh tired eyes.
  • Lipid-Based Drops – Restores the tear film’s oil layer for those with Meibomian gland dysfunction (MGD).

Who Can Benefit?

  • Dry eye sufferers needing frequent eye drop use
  • Individuals with sensitivity to preservatives
  • Post-surgical patients requiring gentle eye care
  • Contact lens wearers seeking safe, long-lasting hydration
  • Anyone looking for a preservative-free solution in a multi-dose format

Pure Hydration, No Preservatives, No Waste
Discover the advantages of our preservative-free eye relief in a convenient, multi-dose bottle. Browse through our Preservative-Free Multi-Dose Eye Drops Collection and find the ideal solution for gentle, effective, and lasting eye comfort!

Showing 1 - 25 of 25 products
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The Optase Intense 2-Pack Preservative Free Eye Drops are displayed with a purple eye graphic. Each box provides long-lasting relief for moderate to severe dry eyes, includes over 300 drops, and features steps: heat, cleanse, hydrate.The Optase Intense 2-pack comes with two boxes and bottles featuring a purple eye graphic. The label emphasizes its preservative-free formula, which preserves moisture and alleviates moderate to severe dry eye symptoms.
$39.95 $49.99
Optase Intense 2-pack Preservative Free Eye Drops 2-PackOptase
Save $1.00
Optase Intense Preservative Free Eye Drops (10mL) by Optase provide preservative-free, long-lasting relief for intense dry eye symptoms, delivering approximately 300 drops. The packaging highlights effectiveness and guides on steps: heat, cleanse, hydrate.The image features an Optase Intense Preservative Free Eye Drops box and bottle, with a purple eye illustration, promising preservative-free, long-lasting relief for dry eyes in a 10mL (0.33 fl oz) sterile solution, ideal for intense symptom relief.
$23.95 $24.95
Optase Intense Preservative Free Eye Drops (10mL) 300 dropsOptase
Save $1.04
Box of Harrow Healths Freshkote (PF) Preservative Free Multidose Eye Drops, offering clear relief for dry eyes in a 10mL bottle with 300 drops, designed to temporarily soothe and comfort irritated eyes.Harrow Healths Freshkote (PF) Preservative Free Multidose Eye Drops offer soothing dry eye relief with a preservative-free formula in a 10mL bottle, featuring The Clear Solution for immediate comfort.
$38.95 $39.99
Freshkote (PF) Preservative Free Multidose Eye Drops 300 drops (10mL)Harrow Health
Save $1.04
The image shows an Oasis Tears Plus Preservative-Free Eye Drops box, by Oasis Medical, for severe dry eye relief. The packaging is mainly white with blue text highlighting relief for dry eyes and specifies the volume as 10ml or 0.34 FL OZ.
$28.95 $29.99
Oasis Tears Plus Preservative-Free Eye Drops (10ml Multi-drop Bottle)Oasis Medical
Save $10.04
Two boxes of Harrow Healths Freshkote PF Lubricant Eye Drops, each 0.33 fl oz (10 mL), promise temporary dry eye relief with a clear, preservative-free solution.Two bottles of Harrow Healths Freshkote PF Lubricant Eye Drops, each 0.33 fl oz (10 mL), are shown with packaging that highlights Temporarily Relieves Symptoms of Dry Eye on a purple background.
$69.95 $79.99
Freshkote Preservative Free (PF) Lubricant Eye Drops (Pack of 2)Harrow Health
Save $6.11
Optase MGD Advanced Eye Drops, preservative-free, 0.33 fl oz, soothe dryness and irritation with DEMET technology and a lipid-based formula for Meibomian Gland Dysfunction. It follows three steps: heat, cleanse, hydrate. The box is mostly white with pink accents.Image of Optase MGD Advanced Eye Drops Preservative-Free 2 Month Supply packaging and bottle. The box, mainly white with red and black text, emphasizes the preservative-free lipid-based formula with DEMET technology for Meibomian Gland Dysfunction relief. The bottle has a yellow cap.
$23.88 $29.99
Optase MGD Advanced Eye Drops Preservative-Free 2 Month Supply (300 drops) (1 Bottle)Optase
Save $10.04
Two Oasis Tears lubricant eye drops bottles are showcased in front of their packaging. Each 10 ml bottle, preservative-free and glycerin-based, is designed by Oasis Medical to relieve dry eyes effectively. The 2-pack includes multi-drop bottles with a total of 600 drops.Two 0.34 fl oz bottles of Oasis Tears 2-pack Preservative-Free Eye Drops by Oasis Medical, labeled as preservative-free with glycerin and sodium hyaluronate for soothing dry eyes, are shown clearly against a plain background with drug facts labels.
$39.95 $49.99
Oasis Tears 2-pack Preservative-Free Eye Drops (Multi-drop Bottle) 2-Pack 600 dropsOasis Medical
Save $5.04
The Regener-Eyes Lite Eye Drops (3mL Bottle, 3-4 Week Supply) features a green and blue droplet logo and promises eye dryness relief, ensuring comfort with every use.
$84.95 $89.99
Regener-Eyes Lite Eye Drops (3mL Bottle, 3-4 Week Supply)Regener-Eyes
Save $4.04
A 10mL bottle of Oasis Tears Preservative-Free Eye Drops by Oasis Medical accompanies its stylish white and silver box, featuring a sodium hyaluronate solution for effective dry eye relief.A 10mL bottle of Oasis Tears Preservative-Free Eye Drops by Oasis Medical offers relief for dry eyes, highlighting sodium hyaluronate as the active ingredient. The Drug Facts label provides details on uses, warnings, and proper use instructions.
$24.95 $28.99
Oasis Tears Preservative-Free Eye Drops (10mL Bottle)Oasis Medical
Save $21.04
Two boxes of Optase MGD 2-pack Advanced Eye Drops are shown, each featuring a pink lid, eye graphic, and details emphasizing its preservative-free formula with DuraTear technology, perfect for relieving dryness and irritation due to Meibomian Gland Dysfunction.Two boxes of Optase MGD 2-pack Advanced Eye Drops provide a preservative-free, DEMET technology solution for Meibomian Gland Dysfunction. Featuring an eye illustration on the red-circled packaging, each 10ml bottle of this 600-drop pack ensures lasting comfort for over 3 months.
$38.95 $59.99
Optase MGD 2-pack Advanced Eye Drops Preservative-Free 3+ Month Supply (600 drops) 2-packOptase
Save $1.00
An image shows a white bottle of Optase Hylo Relief Preservative-Free Eye Drops (300 Drops), designed for easy application, ideal for those with manual dexterity issues. The label has a blue and yellow design, highlighting its preservative-free feature, providing relief from dry eye disease.Optase Hylo Relief Eye Drops, preservative-free and compatible with contact lenses, offer a 300-drop solution for dry eye disease. The design accommodates those with manual dexterity issues for ease of use.
$23.95 $24.95
Optase Hylo Relief Preservative-Free Eye Drops (300 Drops)Optase
Save $1.04
Theas iVIZIA Sterile Lubricant Eye Drops offer preservative-free relief for dry eyes, delivering up to 8 hours of long-lasting hydration. The 10ml bottle is contact lens friendly and features a vibrant rainbow circle design, coherent with its colorful box packaging.The iVIZIA Sterile Lubricant Eye Drops by Thea, a preservative-free solution for lasting dry eye relief, includes a detailed drug facts label with active ingredients, purpose, uses, warnings, directions, inactive ingredients, and contact info for questions (phone/email). Suitable for contact lenses.
$18.95 $19.99
iVIZIA Sterile Lubricant Eye Drops, Preservative-Free, Dry Eye Relief, Contact Lens Friendly, 0.33 fl oz (10ml bottle)Thea
Save $45.14
Three boxes of Regener-Eyes Lite 3-Pack Eye Drops (3 x 3mL bottles, 2-month supply) with a green and blue teardrop logo, promising To Relieve Dryness of the Eye.
$224.85 $269.99
Regener-Eyes Lite 3-Pack Eye Drops (3 x 3mL Bottles, 2 Month Supply)Regener-Eyes
Save $5.99
The Eyeganics 100% Organic Preservative Free Eye Drops for Dry Eyes is presented in a white and blue box with a green leaf design, highlighting its USDA Certified Organic and preservative-free nature. A small bottle sits in front for gentle dry eye relief.
$29.00 $34.99
Eyeganics 100% Organic Preservative Free Eye Drops for Dry EyesEyeganics
Save $1.04
Theas iVIZIA Sterile Lubricant Eye Drops provide dry eye relief, are preservative-free, contact lens friendly, and from Europes #1 doctor-prescribed dry eye brand. Each bottle contains 0.17 fl oz (5 ml).Theas iVIZIA Sterile Lubricant Eye Drops feature packaging beside a 0.17 fl oz (5 ml) bottle, decorated with colorful concentric arcs like an eye. This preservative-free lubricant offers dry eye relief and is safe for contact lenses.
$14.95 $15.99
iVIZIA Sterile Lubricant Eye Drops, Preservative-Free, Contact Lens Friendly, 0.17 fl oz (5ml bottle)Thea
Save $13.04
Theas iVIZIA 2-pack Sterile Lubricant Eye Drops, each being a preservative-free 10ml bottle, provide up to 8 hours of dry eye relief and are safe with contacts.The iVIZIA 2-pack Sterile Lubricant Eye Drops by Thea, preservative-free, provides a drug facts label with active ingredients, purposes, uses, warnings, directions, and inactive ingredients. It includes a helpline for questions and advice on conditions like pregnancy or accidental ingestion. Ideal for dry eye relief.
$26.95 $39.99
iVIZIA 2-pack Sterile Lubricant Eye Drops, Preservative-Free, (2 x 10ml bottle) 2-PackThea
Save $4.04
Image of a box for Abbvies Refresh Relieva Preservative-Free Lubricant Eye Drops (10mL Multi-Dose Bottle) designed for dry eyes, featuring a droplet graphic. Highlights include preservative-free formula, lubrication, protection, and relief from LASIK dryness. Contains 0.33 fl oz sterile drops.The Abbvie Refresh Relieva Preservative-Free Lubricant Eye Drops come in a 10mL white bottle with a green cap. Its vibrant green and blue box highlights Preservative-Free and Lubricates and Protects for Sensitive Eyes, making it soothing for dry eyes.
$19.95 $23.99
Refresh Relieva Preservative-Free Lubricant Eye Drops (10mL Multi-Dose Bottle)Abbvie
Save $3.04
The Alcon Systane Hydration PF Lubricant Eye Drops come in a small 10 ml bottle with a white cap. Featuring sodium hyaluronate, these preservative-free drops offer enhanced relief and soothing for dry eyes.Alcons Systane Hydration PF Lubricant Eye Drops offer dry eye relief in a preservative-free formula. The 10ml bottle matches its blue and green packaging, featuring sodium hyaluronate for soothing and lasting hydration.
$21.95 $24.99
Systane Hydration Pf Lubricant Eye Drops (Preservative Free Multidose Bottle) 10mlAlcon
Save $10.04
Biotrue Hydration Boost Eye Drops by Bausch & Lomb come in a green and white box. This 2-pack provides over 600 drops to soothe dry, irritated eyes with HA, an antioxidant, and electrolyte for instant moisture. Preservative-free and contact lens friendly.Two bottles of Biotrue Hydration Boost Eye Drops by Bausch + Lomb, preservative-free and soft contact lens friendly, feature before the box. It offers instant moisture for dry, irritated eyes with HA, a natural moisturizer, antioxidant, and electrolyte. Each 10 mL bottle provides over 600 drops.
$24.95 $34.99
Biotrue Hydration Boost Eye Drops, Preservative Free, Soft Contact Lens Friendly (10 mL), Pack of 2 (600+ Drops)Bausch + Lomb
Save $17.04
The Optase Intense Preservative Free with Magic Touch Applicator packaging features a purple eye graphic and benefit description for dry eyes relief. The Magic Touch applicator, on the right, includes a blue finger sleeve for easy application of preservative-free eye drops.The Optase Intense Preservative Free with Magic Touch Applicator packaging features eye images and highlights that it provides long-lasting relief. The eye drop box emphasizes product details, while the applicator shows a hand holding it, catering to dry eye needs without preservatives.
$22.95 $39.99
Optase Intense Preservative Free with Magic Touch ApplicatorOptase
Save $40.04
Regener-Eyes Lite with Magic Touch Easy Applicator features packaging highlighting its relief for dry eyes and shows the easy-use applicator on a fingertip near an eye, promising a 4-week supply in a convenient 3mL bottle.The Regener-Eyes Lite ophthalmic solution for eye dryness, featuring a white and green design with a droplet logo, is packaged alongside the Magic Touch Easy Applicator, which displays a blue cone-shaped device with an eye image. This set includes a 3mL bottle providing a 4-week supply.
$59.95 $99.99
Regener-Eyes Lite with Magic Touch Easy Applicator (3mL Bottle, 4 Week Supply)Regener-Eyes
Save $2.04
Refresh Relieva PF Xtra – Advanced Preservative-Free Lubricant Eye Drops (10mL) by Abbvie offers fast-acting relief and advanced hydration for dry, sensitive eyes. Utilizing HydroCell technology with Trehalose, its the #1 doctor-recommended brand.Image of Abbvies Refresh Relieva PF Xtra eye drops box and bottle, featuring its preservative-free formula with trehalose for advanced hydration, designed for dry, sensitive eyes. The green box with blue accents and white bottle with a blue cap highlight its benefits.
$23.95 $25.99
Refresh Relieva PF Xtra – Advanced Preservative-Free Lubricant Eye Drops (10mL Bottle)Abbvie
Save $1.04
A box of Bausch + Lomb Biotrue Hydration Boost Eye Drops (10 mL), preservative-free and contact lens friendly, offers hydration boost and instant moisture for dry eyes with HA, antioxidants, and electrolytes.Image of Biotrue Hydration Boost Eye Drops by Bausch + Lomb, emphasizing instant moisture and preservative-free benefits for dry eyes. A clear bottle with a green label is positioned next to the light green box, offering soothing relief.
$18.95 $19.99
Biotrue Hydration Boost Eye Drops, Preservative Free, Soft Contact Lens Friendly (10 mL)Bausch + Lomb
Save $5.04
CorneaCares Recover Preservative-Free Artificial Tears promise relief for dry, irritated eyes with a sterile solution. The white box emphasizes See Relief, delivering comfort in a 10mL multi-dose bottle.A small bottle of CorneaCare Recover Preservative-Free Artificial Tears (10mL Multi-Dose Bottle) is beside its packaging. The white box and bottle feature blue waves and text, highlighting advanced hydration and soothing relief for dry, irritated eyes. The cap rests in front.
$19.95 $24.99
Cornea Care Recover Preservative-Free Artificial Tears – Advanced Hydration & Soothing Relief for Dry, Irritated Eyes (10mL Multi-Dose Bottle)CorneaCare
Save $2.04
The packaging for Abbvies Refresh Tears PF Preservative-Free Eye Drops (10mL) features a Preservative-Free Artificial Tears formula, a #1 Doctor Recommended seal, and promises Original Strength Plus Protection for Dry, Sensitive Eyes in a convenient multidose bottle with fast-acting relief.The image features a 10mL multidose bottle and box of Refresh Tears PF Preservative Free Eye Drops by Abbvie. The green and blue packaging promises fast-acting, original strength moisturizing relief and protection for dry, sensitive eyes.
$17.95 $19.99
Refresh Tears PF Preservative Free Eye Drops (10mL)Abbvie

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